Yu-Lin (Katherine) Ma
Identification of Molecular Factors Regulating Fat Cell Biology
Our previous studies led to identification of a set of genes that are selectively expressed in fat precursor cells. I will study whether these candidate genes regulate differentiation and metabolic function of fat cells by performing gain- and loss-of function studies. Measured outcomes include lipid accumulation, fat cell-specific gene expression, insulin-stimulated glucose uptake and insulin signaling assay. This study will reveal novel molecular factors regulating fat cell biology.