Jane Lin
Role of Vitamin D in Carcinogenesis
By knocking out Vitamin D Receptor (VDR) gene and Calcium Sensing Receptor (Casr) genes, we created Double Knockout mice (DKO). After 12 months, these mice spontaneously develop squamous cell carcinoma (SCC), as supported by precious histology analysis of the tumor sections. In the summer, I will analyze gene expressions and stem cell trajectories of specific genes related to carcinogenesis and epidermis cells via single cell sequencing.
Message To Sponsor
Thank you for your generous donation! I have worked on this project for more than a year now, and it is very meaningful to wrap it up and help with paper publication in the summer!
Major: Integrative Biology, Music
Mentor: UCSF VA Medical Center, Endocrine Department - Yuko Oda
Sponsor: Leadership Fund