Sravya Chilukuri Rose Hills
Confirming the Presence of Functional CatSper Ion Channels in Primate and Rat Sperm Cells
There is an abundance of what humans consider to be pest animals in the world, such as a high population of rats or an uncontrollable populace of monkeys. These pest animals can often act as vectors for disease and they can damage property or endanger human life. It is crucial to control these growing populations in order to avoid these problems. One major way to control population growth is through effective and humane methods of sterilization. I intend to do this by creating an antibody vaccine against the principal calcium ion channel of sperm, CatSper. However in order to create a successful vaccine, it is crucial to first confirm the actual presence and functionality of CatSper in monkeys and rats, which is what my project aims to achieve. Through this project, I hope to lay the foundation for creating a sterilization vaccine to combat these excessive populations of pest animals.