Undergraduate Research & Scholarships

Kevin Yao L&S Biological Sciences

Unraveling the Molecular Activation of Kidney Regeneration

Chronic Kidney Disease (CKD) is one of the most common diseases among American adults. As one of the essential organs to maintain life, deprived renal functions lead to disruptions of homeostasis and fatal failures of the body. The prevalence of CKD is associated closely with the lack of renal regeneration capacity in the adult human body. However, recent study has shown that this inability of regeneration is not innate but an acquired process in mammals like humans. Many newborn mammals are reported to have full renal regeneration capacity while such is completely lost when they reach adult stage. The molecular evidence during mammal’s development, such as changes in genetic regulations, indicates the mechanism of activation and inhibition of renal regeneration. Hence, this project surveys on identifying novel transcription factors that drive kidney regeneration during mammal development, which may suggest new ways in reversing kidney injury and curing CKD.

Message To Sponsor

A big thank you to all the donors who made this opportunity possible. Your contributionsc allow me to dive into molecular biology, exploring the possiblity of kidney regeneration. I feel very honored to be part of this program, and I'm extremely grateful for your great support and vision in advancing biological science!
Major: Molecular and Cell Biology and Computer Science
Mentor: Guo Huang
Sponsor: Shin Morgan Fund
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