Joshua Kane L&S Sciences
Characterizing the Formation and Phylogenetic History of an 81-Member Tandem Duplicated Pre-tRNA Gene Cluster in Arabidopsis thaliana
My research fuses the disciplines of genomics and phylogenetics in order to characterize the evolution of large gene arrays. My research focuses on an eighty-one member pre-tRNA gene array located on chromosome one of Arabidopsis thaliana. The array itself is subdivided into twenty-seven triplet gene units, each triplet consisting of a single pre-tRNASer gene and two pre-tRNATyr genes, respectively. Using genomic data, such as syntenic analysis with outgroup species, and phylogenetic reconstruction of the evolutionary history of the genes in the array, my research aims to elucidate the history of the arrays formation, and the mechanism that formed, or equally-possible mechanisms that would have formed, the array as it exists today.