Agamjot Bal L&S Biological Sciences
Producing Dengue virus recombinant non-structural protein 1 (NS1)
My project focuses on the production of recombinant NS1 of DENV1-4 and ZIKV strains from Nicaragua. These proteins will be used to investigate whether the antibody profile against NS1 is associated with DENV2 infection outcome in samples from the Nicaraguan Pediatric Dengue Cohort Study. Creating NS1 in this way will allow for proper protein folding, capture of the protein during purification, and assistance with coupling to microspheres for the Luminex analysis. This will provide further insights into NS1’s role in dengue infections and possibly open new avenues for in-house protein production.
Message To Sponsor
Thank you to (donor) for their generosity and help with keeping projects like mine going. As an undergraduate, research experience isn't always the easiest thing to come by. As an undergraduate researcher, funding and programs like SURF are far and few between. Thank you for giving people like myself the opportunity and means to pursue our interests in science and beyond.Major: Molecular and Cell Biology, Slavic Languages and Literatures
Mentor: Eva Harris
Sponsor: Pergo