Undergraduate Research & Scholarships

Nancy Thi

Chemosensory Adaptations to Toxic Compounds in Drosophilids

Plants produce toxic chemicals to protect themselves from being eaten by insects. In response, many insects have evolved ways to detect and tolerate these toxins. In this project, we use the model fruit fly Drosophila melanogaster to study how flies sense harmful compounds. We focus on different versions of a sensory protein called TRPA1, which helps flies detect these chemicals. By testing how these TRPA1 variants function in the fly’s taste system and nervous system, we aim to understand how insects recognize and respond to plant toxins.

Message To Sponsor

I developed a greater appreciation for the process of scientific research, from conducting assays to troubleshooting unexpected results and interpreting variation across different fly populations. Working with fruit flies has shown me how a simple model organism can help us investigate complex biological processes, particularly how organisms respond to their environment. I also had the opportunity to train another undergraduate researcher, which strengthened my own understanding while allowing me to pass on the skills I developed. This experience has been meaningful for my growth as a student and scientist.